2079. The Relation Between Panel Reactive Antibody Assay and Cytomegalovirus Reactivation in Seropositive Solid Organ Transplantation Recipients

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Cytomegalovirus in solid organ transplant recipients.

CMV infection is a major cause of morbidity in patients receiving solid organ transplants. CMV is widely distributed in the general population with seroprevalence ranging from 30 to 97% (1–3). After primary infection, CMV establishes life-long latency. Without some form of prevention, CMV infection primarily occurs in the first 3 months following transplant. Onset may be delayed in patients rec...

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Importance of the cytomegalovirus seropositive recipient as a contributor to disease burden after solid organ transplantation

BACKGROUND The incidence of cytomegalovirus (CMV) syndrome/disease after adult solid organ transplantation in the era effective antiviral therapy has not been fully assessed. OBJECTIVE To determines the incidence of CMV syndrome/disease after solid organ transplantation in the UK. STUDY DESIGN A retrospective analysis of 1807 solid organ transplants from 12 UK solid organ transplant centres...

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Human Cytomegalovirus Infection in Solid-Organ Transplantation

Human cytomegalovirus (CMV) continues to be a major threat against solid-organ transplant recipients despite significant advancements in its prophylaxis and therapy. Primary CMV infection or reactivation of latent CMV in the transplant recipients may cause CMV diseases such as flu-like viral syndrome and tissue-invasive CMV disease. In addition, CMV infection in the recipients is associated wit...

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Cytomegalovirus infection in solid organ transplantation.

Cytomegalovirus infection remains a serious threat to solid transplant recipients. Despite advances in this field, there are still difficulties in the diagnosis of the disease and there are questions about the best and most cost-effective strategy to prevent infection and its direct and indirect consequences in the short and long term. All these points are discussed and updated in this chapter.

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Monitoring of cytomegalovirus infection in solid-organ transplant recipients by an ultrasensitive plasma PCR assay.

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ژورنال

عنوان ژورنال: Open Forum Infectious Diseases

سال: 2018

ISSN: 2328-8957

DOI: 10.1093/ofid/ofy210.1735